In the early moing, at the Gen research building, the cleaner accidentally opened the iron cage in the laboratory and was killed by the "hidden" animal. To investigate the origin of the strange python, A Luong, a wildlife biologist, went to the Gen corporation where his ex-girlfriend Thi Van worked. When Thi Van took A Luong to observe the company, he was attacked by a tyrannosaur, everyone had to flee to the security room.

A Luong discovers that the so-called "monster" is made of mixed genes, so they must not only escape the monster';s attack, but also obtain all the data of the set. Gen group. The mutant Tyrannosaurus rex is extremely ferocious, not only large in size, but also changing skin color like a chameleon, causing many people to die. A Luong found that although the tyrannosaur was fierce, it still had the weakness of the chameleon, which was afraid of the cold.

Even so, A Luong alone could not withstand such a dinosaur, A Luong devised a way to use mutant giant pythons to fight the mutant Tyrannosaurus rex, and at the same time find himself a breakthrough. Destroy the Tyrannosaurus Rex.